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SATB2 targeted by methylated miR‐34c‐5p suppresses proliferation and metastasis attenuating the epithelial‐mesenchymal transition in colorectal cancer

OBJECTIVES: SATB2 has been shown to be markedly reduced in colorectal cancer (CRC) tissues relative to paired normal controls; however, the mechanism behind remains not well understood. To investigate why SATB2 was down‐regulated in CRC, we attempted to analyse it from the angle of miRNA‐mRNA modula...

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Vydáno v:Cell Prolif
Hlavní autoři: Gu, Jingfeng, Wang, Guiqi, Liu, Haixia, Xiong, Chaohui
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528935/
https://ncbi.nlm.nih.gov/pubmed/29701273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12455
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