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miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2

A screen of microRNAs preferentially expressed in osteoblasts identified members of the miR-34 family as regulators of osteoblast proliferation and/or differentiation. Osteoblast-specific gain- and loss-of-function experiments performed in vivo revealed that miR-34b and -c affected skeletogenesis du...

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Detalhes bibliográficos
Main Authors: Wei, Jianwen, Shi, Yu, Zheng, Lihua, Zhou, Bin, Inose, Hiroyuki, Wang, Ji, Guo, X. Edward, Grosschedl, Rudolf, Karsenty, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352956/
https://ncbi.nlm.nih.gov/pubmed/22564414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201057
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