HYDROXYMETHYLATION AND DNA METHYLATION PROFILES IN THE PREFRONTAL CORTEX OF THE NON-HUMAN PRIMATE RHESUS MACAQUE AND THE IMPACT OF MATERNAL DEPRIVATION ON HYDROXYMETHYLATION

5-Hydroxymethylcytosine (5hmC) is abundant in the brain, suggesting an important role in epigenetic control of neuronal functions. In this paper, we show that 5hmC and 5-methylcytosine (5mC) levels are coordinately distributed in gene promoters of the rhesus macaque prefrontal cortex. Although promo...

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Pubblicato in:Neuroscience
Autori principali: MASSART, R., SUDERMAN, M., PROVENCAL, N., YI, C., BENNETT, A. J., SUOMI, S., SZYF, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528794/
https://ncbi.nlm.nih.gov/pubmed/24657458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.03.021
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