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Enantioselective Organocatalytic Amine-Isocyanate Capture-Cyclization: Regioselective Alkene Iodoamination for the Synthesis of Chiral Cyclic Ureas

Ureas of chiral diamines are prominent features of therapeutics, chiral auxiliaries, and intermediates in complex molecule synthesis. Although many methods for diamine synthesis are available, metal-free enantioselective alkene functionalizations to make protected 1,2- and 1,3-diamines from simple a...

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Detalles Bibliográficos
Publicado en:ACS Catal
Main Authors: Struble, Thomas J., Lankswert, Hannah M., Pink, Maren, Johnston, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528665/
https://ncbi.nlm.nih.gov/pubmed/31131150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b03708
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