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Brønsted Acid Catalyzed Phosphoramidic Acid Additions to Alkenes: Diastereo- and Enantioselective Halogenative Cyclizations for the Synthesis of C- and P-Chiral Phosphoramidates

[Image: see text] The first highly diastereo- and enantioselective additions of a halogen and phosphoramidic acid to unactivated alkenes have been developed, catalyzed by a chiral Brønsted acid. A unique feature of these additions is the opportunity for stereocontrol at two noncontiguous chiral cent...

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Detalhes bibliográficos
Main Authors: Toda, Yasunori, Pink, Maren, Johnston, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210055/
https://ncbi.nlm.nih.gov/pubmed/25336273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5088584
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