Sevoflurane post-conditioning alleviates neonatal rat hypoxic-ischemic cerebral injury via Ezh2-regulated autophagy

Background: When neonatal rats suffer hypoxic-ischemic brain injury (HIBI), autophagy is over-activated in the hippocampus, and inhibition of autophagy provides neuroprotection. The aim of this study was to investigate the possible roles of autophagy and Ezh2-regulated Pten/Akt/mTOR pathway in sevof...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Xue, Hang, Xu, Ying, Wang, Shuo, Wu, Zi-Yi, Li, Xing-Yue, Zhang, Ya-Han, Niu, Jia-Yuan, Gao, Qiu-Shi, Zhao, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528650/
https://ncbi.nlm.nih.gov/pubmed/31190748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S197325
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