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Par3 regulates polarized convergence between APP and BACE1 in hippocampal neurons
The convergence between amyloid precursor protein (APP) and its β-secretase β-site APP cleaving enzyme 1 (BACE1) is a prerequisite for the generation of β-amyloid peptide, a key pathogenic agent for Alzheimer’s disease. Yet the underlying molecular mechanisms regulating their convergence remain uncl...
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| Publicado no: | Neurobiol Aging |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528466/ https://ncbi.nlm.nih.gov/pubmed/30784815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.01.023 |
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