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Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells

BACKGROUND: Cisplatin is one of the most widely used chemotherapeutic agents, but its efficacy is limited by its side effects. Hence, it is of great significance to develop novel agents to synergize with cisplatin and decrease side effects. In our previous study, we demonstrated that WZ35, a novel c...

詳細記述

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: He, Wei, Xia, Yiqun, Cao, Peihai, Hong, Lin, Zhang, Tingting, Shen, Xin, Zheng, Peisen, Shen, Huanpei, Liang, Guang, Zou, Peng
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528260/
https://ncbi.nlm.nih.gov/pubmed/31113439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1215-y
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