Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells

BACKGROUND: Cisplatin is one of the most widely used chemotherapeutic agents, but its efficacy is limited by its side effects. Hence, it is of great significance to develop novel agents to synergize with cisplatin and decrease side effects. In our previous study, we demonstrated that WZ35, a novel c...

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Publicat a:J Exp Clin Cancer Res
Autors principals: He, Wei, Xia, Yiqun, Cao, Peihai, Hong, Lin, Zhang, Tingting, Shen, Xin, Zheng, Peisen, Shen, Huanpei, Liang, Guang, Zou, Peng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528260/
https://ncbi.nlm.nih.gov/pubmed/31113439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1215-y
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