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Multiplexed CRISPR/Cas9 gene knockout with simple crRNA:tracrRNA co-transfection

BACKGROUND: CRISPR/Cas9 mediated gene knockout is a powerful tool for genome editing with the ability to target multiple genes simultaneously. Establishing an efficient, multiplexed gene knockout system using CRISPR/Cas9 that is both simple and robust in its application would further advance the ado...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Khan, Fehad J., Yuen, Garmen, Luo, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528186/
https://ncbi.nlm.nih.gov/pubmed/31139343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0304-0
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