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The Oncogene IARS2 Promotes Non-small Cell Lung Cancer Tumorigenesis by Activating the AKT/MTOR Pathway

A limited number of studies have indicated an association between isoleucyl-tRNA synthetase 2 (IARS2) and tumorigenesis. We evaluated IARS2 protein expression in lung tumor tissues and paired non-tumor tissues. We found higher IARS2 expression in the tumor tissues, which was associated with the late...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Di, Xin, Jin, Xin, Ma, He, Wang, Ruimin, Cong, Shan, Tian, Chang, Liu, Jiaying, Zhao, Min, Li, Ranwei, Wang, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528107/
https://ncbi.nlm.nih.gov/pubmed/31157169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00393
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