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Major Contribution of Somatostatin-Expressing Interneurons and Cannabinoid Receptors to Increased GABA Synaptic Activity in the Striatum of Huntington’s Disease Mice
Huntington’s disease (HD) is a heritable neurological disorder that affects cognitive and motor performance in patients carrying the mutated huntingtin (HTT) gene. In mouse models of HD, previous reports showed a significant increase in spontaneous GABA(A) receptor-mediated synaptic activity in stri...
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| Udgivet i: | Front Synaptic Neurosci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527892/ https://ncbi.nlm.nih.gov/pubmed/31139071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2019.00014 |
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