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Melatonin ameliorates endoplasmic reticulum stress in N2a neuroblastoma cell hypoxia-reoxygenation injury by activating the AMPK-Pak2 pathway

Endoplasmic reticulum (ER) stress has been identified as a primary factor involved in brain ischemia-reperfusion injury progression. p21-activated kinase 2 (Pak2) is a novel ER function regulator. The aim of our study is to explore the influence of Pak2 on ER stress and determine whether melatonin a...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Xing, Jin, Xu, Hao, Liu, Chaobo, Wei, Zilong, Wang, Zhihan, Zhao, Liang, Ren, Li
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527732/
https://ncbi.nlm.nih.gov/pubmed/30976981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-00994-0
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