Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and highly lethal lung disease with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis mostly due to respiratory failure. Current treatments against IPF aim to ameliorate patient symptoms and to delay di...

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Publicado no:Nat Commun
Main Authors: Rubio, Karla, Singh, Indrabahadur, Dobersch, Stephanie, Sarvari, Pouya, Günther, Stefan, Cordero, Julio, Mehta, Aditi, Wujak, Lukasz, Cabrera-Fuentes, Hector, Chao, Cho-Ming, Braubach, Peter, Bellusci, Saverio, Seeger, Werner, Günther, Andreas, Preissner, Klaus T., Wygrecka, Malgorzata, Savai, Rajkumar, Papy-Garcia, Dulce, Dobreva, Gergana, Heikenwalder, Mathias, Savai-Pullamsetti, Soni, Braun, Thomas, Barreto, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527704/
https://ncbi.nlm.nih.gov/pubmed/31110176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10066-7
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