Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin

Celiac Disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins. Some gliadin peptides (e.g., A-gliadin P57-68) induce an adaptive Th1 pro-inflammatory response. Other gliadin peptides (e.g., A-gliadin P31-43) induce a s...

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Publicat a:Commun Biol
Autors principals: Lania, Giuliana, Nanayakkara, Merlin, Maglio, Mariantonia, Auricchio, Renata, Porpora, Monia, Conte, Mariangela, De Matteis, Maria Antonietta, Rizzo, Riccardo, Luini, Alberto, Discepolo, Valentina, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527696/
https://ncbi.nlm.nih.gov/pubmed/31123714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0443-1
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