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P31–43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease

Celiac disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins. Some gliadin peptides are resistant to intestinal digestion (e.g., A-gliadin P31–43) and induce a stress/innate immune response, but the reason why they ar...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Nanayakkara, Merlin, Lania, Giuliana, Maglio, Mariantonia, Auricchio, Renata, De Musis, Cristiana, Discepolo, Valentina, Miele, Erasmo, Jabri, Bana, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050301/
https://ncbi.nlm.nih.gov/pubmed/30018339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28830-y
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