P31–43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease

Celiac disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins. Some gliadin peptides are resistant to intestinal digestion (e.g., A-gliadin P31–43) and induce a stress/innate immune response, but the reason why they ar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nanayakkara, Merlin, Lania, Giuliana, Maglio, Mariantonia, Auricchio, Renata, De Musis, Cristiana, Discepolo, Valentina, Miele, Erasmo, Jabri, Bana, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050301/
https://ncbi.nlm.nih.gov/pubmed/30018339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28830-y
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