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Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells

The large pore ion channel pannexin-1 (Panx1) has been reported to play a role in the cellular uptake and release of anandamide (AEA) in the hippocampus. It is not known whether this is a general mechanism or limited to the hippocampus. We have investigated this pharmacologically using T84 colon can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Alhouayek, Mireille, Sorti, René, Gilthorpe, Jonathan D., Fowler, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527687/
https://ncbi.nlm.nih.gov/pubmed/31110238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44057-x
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