Identifying the murine mammary cell target of metformin exposure

The heterogeneity of breast cancer makes current therapies challenging. Metformin, the anti-diabetic drug, has shown promising anti-cancer activities in epidemiological studies and breast cancer models. Yet, how metformin alters the normal adult breast tissue remains elusive. We demonstrate metformi...

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Udgivet i:Commun Biol
Main Authors: Shehata, Mona, Kim, Hyeyeon, Vellanki, Ravi, Waterhouse, Paul D., Mahendralingam, Mathepan, Casey, Alison E., Koritzinsky, Marianne, Khokha, Rama
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527562/
https://ncbi.nlm.nih.gov/pubmed/31123716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0439-x
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