Model-based understanding of single-cell CRISPR screening

The recently developed single-cell CRISPR screening techniques, independently termed Perturb-Seq, CRISP-seq, or CROP-seq, combine pooled CRISPR screening with single-cell RNA-seq to investigate functional CRISPR screening in a single-cell granularity. Here, we present MUSIC, an integrated pipeline f...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Duan, Bin, Zhou, Chi, Zhu, Chengyu, Yu, Yifei, Li, Gaoyang, Zhang, Shihua, Zhang, Chao, Ye, Xiangyun, Ma, Hanhui, Qu, Shen, Zhang, Zhiyuan, Wang, Ping, Sun, Shuyang, Liu, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527552/
https://ncbi.nlm.nih.gov/pubmed/31110232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10216-x
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