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A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer

Small cell lung cancer (SCLC) is the most aggressive neuroendocrine phenotype of the deadliest human lung cancers. However the therapeutic landscape for SCLC has not changed in over 30 years. Effective treatment and prognosis are needed to combat this aggressive cancer. Herein we report that Ser/Arg...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Shimojo, Masahito, Kasahara, Yuuya, Inoue, Masaki, Tsunoda, Shin-ichi, Shudo, Yoshie, Kurata, Takayasu, Obika, Satoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527545/
https://ncbi.nlm.nih.gov/pubmed/31110284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43100-1
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