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A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer

Small cell lung cancer (SCLC) is the most aggressive neuroendocrine phenotype of the deadliest human lung cancers. However the therapeutic landscape for SCLC has not changed in over 30 years. Effective treatment and prognosis are needed to combat this aggressive cancer. Herein we report that Ser/Arg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Shimojo, Masahito, Kasahara, Yuuya, Inoue, Masaki, Tsunoda, Shin-ichi, Shudo, Yoshie, Kurata, Takayasu, Obika, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527545/
https://ncbi.nlm.nih.gov/pubmed/31110284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43100-1
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