Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation Transfer Echo-Planar Imaging and Dynamic Susceptibility Contrast Perfusion MRI at 3T

BACKGROUND AND PURPOSE: Acidification of the tumor microenvironment from abnormal metabolism along with angiogenesis to meet metabolic demands are both hallmarks of malignant brain tumors; however, the interdependency of tumor acidity and vascularity has not been explored. Therefore, our aim was to...

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Detalhes bibliográficos
Publicado no:AJNR Am J Neuroradiol
Main Authors: Wang, Y.-L., Yao, J., Chakhoyan, A., Raymond, C., Salamon, N., Liau, L.M., Nghiemphu, P.L., Lai, A., Pope, W.B., Nguyen, N., Ji, M., Cloughesy, T.F., Ellingson, B.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Neuroradiology 2019
Assuntos:
Adult Brain
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527337/
https://ncbi.nlm.nih.gov/pubmed/31097430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A6063
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