Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange

BACKGROUND AND PURPOSE: Contrast agent extravasation through a disrupted blood-brain barrier potentiates inaccurate DSC MR imaging estimation of relative CBV. We explored whether incorporation of an interstitial washout rate in a leakage-correction model for single-echo, gradient-echo DSC MR imaging...

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Detalles Bibliográficos
Publicado en:AJNR Am J Neuroradiol
Main Authors: Leu, K., Boxerman, J.L., Cloughesy, T.F., Lai, A., Nghiemphu, P.L., Liau, L.M., Pope, W.B., Ellingson, B.M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Neuroradiology 2016
Assuntos:
Adult Brain
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983482/
https://ncbi.nlm.nih.gov/pubmed/27079371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A4759
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