The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin

In addition to large plexiform neurofibromas (pNF), NF1 patients are frequently disfigured by cutaneous neurofibromas (cNF) and are often afflicted with chronic pain and itch even from seemingly normal skin areas. Both pNFs and cNF consist primarily of benign hyperproliferating nonmyelinating Schwan...

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Publicado en:PLoS One
Main Authors: Rice, Frank L., Houk, George, Wymer, James P., Gosline, Sara J. C., Guinney, Justin, Wu, Jianqiang, Ratner, Nancy, Jankowski, Michael P., La Rosa, Salvo, Dockum, Marilyn, Storey, James R., Carroll, Steven L., Albrecht, Phillip J., Riccardi, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527217/
https://ncbi.nlm.nih.gov/pubmed/31107888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216527
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