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Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis

We present a system-level analysis of proteome, phosphoproteome, and chromatin state of precursors of muscle cells (myoblasts) differentiating into specialized myotubes. Using stable isotope labeling of amino acids in cell culture and nano-liqud chromatography-mass spectrometry/mass spectrometry, we...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Bhanu, Natarajan V., Sidoli, Simone, Yuan, Zuo-Fei, Molden, Rosalynn C., Garcia, Benjamin A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527175/
https://ncbi.nlm.nih.gov/pubmed/30872405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004977
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