The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

Histone chaperones affect chromatin structure and gene expression through interaction with histones and RNA polymerase II (PolII). Here, we report that the histone chaperone Spt6 counteracts H3K27me3, an epigenetic mark deposited by the Polycomb Repressive Complex 2 (PRC2) and associated with transc...

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Bibliographische Detailangaben
Hauptverfasser: Wang, A Hongjun, Zare, Hossein, Mousavi, Kambiz, Wang, Chaochen, Moravec, Cara E, Sirotkin, Howard I, Ge, Kai, Gutierrez-Cruz, Gustavo, Sartorelli, Vittorio
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630356/
https://ncbi.nlm.nih.gov/pubmed/23503590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.54
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