Загрузка...
Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4
Cytochrome P450 (CYP) 3A4 is a major contributor to hepatic drug and xenobiotic metabolism in human adults. The related enzyme CYP3A5 is also expressed in adult liver and has broader age and tissue distributions. However, CYP3A5 expression is low in most Caucasians because of the prevalence of an al...
Сохранить в:
| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2019
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527174/ https://ncbi.nlm.nih.gov/pubmed/30926609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007928 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|