A Platform for the Discovery of New Macrolide Antibiotics

The chemical modification of structurally complex fermentation products, a process known as semisynthesis, has been an important tool for the discovery and manufacture of antibiotics for the treatment of various infectious diseases. However, many of the therapeutics obtained in this way are no longe...

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Vydáno v:Nature
Hlavní autoři: Seiple, Ian B., Zhang, Ziyang, Jakubec, Pavol, Langlois-Mercier, Audrey, Wright, Peter M., Hog, Daniel T., Yabu, Kazuo, Allu, Senkara Rao, Fukuzaki, Takehiro, Carlsen, Peter N., Kitamura, Yoshiaki, Zhou, Xiang, Condakes, Matthew L., Szczypiński, Filip T., Green, William D., Myers, Andrew G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526944/
https://ncbi.nlm.nih.gov/pubmed/27193679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17967
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