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Pharmacological Inhibition of GPR4 remediates intestinal inflammation in a mouse colitis model

Inflammatory bowel disease (IBD) is characterized by chronic, recurring inflammation of the digestive tract. Current therapeutic approaches are limited and include biologics and steroids such as anti-TNFα monoclonal antibodies and corticosteroids, respectively. Significant adverse drug effects can o...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Sanderlin, Edward J., Marie, Mona, Velcicky, Juraj, Loetscher, Pius, Yang, Li V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526936/
https://ncbi.nlm.nih.gov/pubmed/30930250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2019.03.038
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