USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy

ULK1 (unc-51 like autophagy activating kinase 1) is a core component at multiple steps of canonical macroautophagy/autophagy. The activity of ULK1 is tightly regulated by several post-translational modifications, including ubiquitination, yet the deubiquitinase (DUB) responsible for its reversible d...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Raimondi, Marzia, Cesselli, Daniela, Di Loreto, Carla, La Marra, Francesco, Schneider, Claudio, Demarchi, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526860/
https://ncbi.nlm.nih.gov/pubmed/30335599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1535291
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