Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR

Macroautophagy/autophagy dysfunction is associated with many neurodegenerative diseases. TFEB (transcription factor EB), an important molecule that regulates lysosomal and autophagy function, is regarded as a potential target for treating some neurodegenerative diseases. However, the relationship be...

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Publicat a:Autophagy
Autors principals: Ye, Bin, Wang, Quan, Hu, Haixia, Shen, Yilin, Fan, Cui, Chen, Penghui, Ma, Yan, Wu, Hao, Xiang, Mingliang
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526833/
https://ncbi.nlm.nih.gov/pubmed/30706760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1569926
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