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C9orf72-dependent lysosomal functions regulate epigenetic control of autophagy and lipid metabolism

Cellular adaption to nutrient stress is exquisitely regulated, and its dysregulation could underlie human diseases including neurodegeneration. C9orf72 is linked to the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) as well as rare cases of other neurologi...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Liu, Yang, Wang, Jiou
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526819/
https://ncbi.nlm.nih.gov/pubmed/30767689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1580106
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