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Expression of Lymphocyte-Activation Gene 3 (LAG-3) Immune Checkpoint Receptor Identifies a Tumor-Reactive T Cell Population in the Peripheral Blood of Patients with Colorectal Cancer

BACKGROUND: The use of adoptive T cell therapy has proven to be effective in some advanced malignancies. This study aimed to investigate the effects of lymphocyte-activation gene 3 (LAG-3) immune checkpoint receptor in the enrichment of tumor antigen-specific CD8(+) T lymphocytes derived from periph...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Huang, Lefu, Qiao, Guoliang, Wu, Jiangping, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526744/
https://ncbi.nlm.nih.gov/pubmed/31077581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915741
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