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Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats

Maprotiline, a tetracyclic antidepressant, is used for the management of mental disorders and various types of chronic pain. In our previous work, we found the inhibitory effect of maprotiline on inflammatory mediator’s expression like tumor necrosis factor α (TNF-α and interleukin 1β (IL-1β. As par...

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Detaylı Bibliyografya
Yayımlandı:Cent Eur J Immunol
Asıl Yazarlar: Rafiee, Laleh, Hajhashemi, Valiollah, Javanmard, Shaghayegh Haghjooy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Polish Society of Experimental and Clinical Immunology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526590/
https://ncbi.nlm.nih.gov/pubmed/31114432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceji.2019.84011
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