Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats

Maprotiline, a tetracyclic antidepressant, is used for the management of mental disorders and various types of chronic pain. In our previous work, we found the inhibitory effect of maprotiline on inflammatory mediator’s expression like tumor necrosis factor α (TNF-α and interleukin 1β (IL-1β. As par...

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Bibliografiska uppgifter
I publikationen:Cent Eur J Immunol
Huvudupphovsmän: Rafiee, Laleh, Hajhashemi, Valiollah, Javanmard, Shaghayegh Haghjooy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Polish Society of Experimental and Clinical Immunology 2019
Ämnen:
Experimental Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526590/
https://ncbi.nlm.nih.gov/pubmed/31114432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceji.2019.84011
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