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Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats

Maprotiline, a tetracyclic antidepressant, is used for the management of mental disorders and various types of chronic pain. In our previous work, we found the inhibitory effect of maprotiline on inflammatory mediator’s expression like tumor necrosis factor  (TNF-) and interleukin 1β (IL-1β). As p...

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Detalhes bibliográficos
Main Authors: Laleh Rafiee, Valiollah Hajhashemi, Shaghayegh Haghjooy Javanmard
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2019-04-01
Colecção:Central European Journal of Immunology
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Acesso em linha:https://www.termedia.pl/Maprotiline-inhibits-COX2-and-iNOS-gene-expression-in-lipopolysaccharide-stimulated-U937-macrophages-and-carrageenan-induced-paw-edema-in-rats,10,36200,1,1.html
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