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3D Telomere Structure Analysis to Detect Genomic Instability and Cytogenetic Evolution in Myelodysplastic Syndromes

The disease course of myelodysplastic syndromes (MDS) features chromosome instability and clonal evolution, leading to the sequential acquisition of novel cytogenetic aberrations and the accumulation of these abnormalities in the bone marrow. Although clonal cytogenetic abnormalities can be detected...

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Publicado en:Cells
Main Authors: Rangel-Pozzo, Aline, de Souza, Daiane Corrêa, Schmid-Braz, Ana Teresa, de Azambuja, Ana Paula, Ferraz-Aguiar, Thais, Borgonovo, Tamara, Mai, Sabine
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526472/
https://ncbi.nlm.nih.gov/pubmed/30987070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040304
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