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Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

Chromosomal instability (CIN), defined by an elevated frequency of the occurrence of novel chromosomal aberrations, is strongly implicated in the generation of aneuploidy, one of the hallmarks of human cancers. As for aneuploidy itself, the role of CIN in the evolution and progression of malignancy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Heilig, Christoph E, Löffler, Harald, Mahlknecht, Ulrich, Janssen, Johannes WG, Ho, Anthony D, Jauch, Anna, Krämer, Alwin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823121/
https://ncbi.nlm.nih.gov/pubmed/19754665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00905.x
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