SF3B1 mutation predicts unfavorable treatment-free survival in Chinese chronic lymphocytic leukemia patients

BACKGROUND: Splicing factor 3b subunit 1 (SF3B1), a splicing factor modulating RNA alternative splicing, is frequently mutated in multiple hematological malignancies including myelodysplastic syndromes and chronic lymphocytic leukemia (CLL). The clinical impact of SF3B1 mutation on CLL remains contr...

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Bibliografiske detaljer
Udgivet i:Ann Transl Med
Main Authors: Miao, Yi, Zou, Yi-Xin, Gu, Dan-Ling, Zhu, Hong-Cheng, Zhu, Hua-Yuan, Wang, Li, Liang, Jin-Hua, Xia, Yi, Wu, Jia-Zhu, Shao, Chun-Lin, Fan, Lei, Zhang, Zhen, Xu, Wei, Li, Jian-Yong
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526254/
https://ncbi.nlm.nih.gov/pubmed/31168457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.03.63
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