NOTCH1 mutation and its prognostic significance in Chinese chronic lymphocytic leukemia: a retrospective study of 317 cases

The proto‐oncogene NOTCH1 is frequently mutated in around 10% of patients with chronic lymphocytic leukemia (CLL). This study analyzed NOTCH1 mutation status of 317 Chinese patients with CLL by Sanger sequencing. The frequencies of NOTCH1 mutation in the PEST (proline (P), glutamic acid (E), serine...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Zou, Yixin, Fan, Lei, Xia, Yi, Miao, Yi, Wu, Wei, Cao, Lei, Wu, Jiazhu, Zhu, Huayuan, Qiao, Chun, Wang, Li, Xu, Wei, Li, Jianyong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Clinical Cancer Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943423/
https://ncbi.nlm.nih.gov/pubmed/29573199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1396
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