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The Predominant Prognostic Significance of NOTCH1 Mutation Defined by Emulsion PCR in Chronic Lymphocytic Leukemia

PURPOSE: NOTCH1(mut) represents a new prognostic marker in chronic lymphocytic leukaemia (CLL). The low sensitivity of the current methods may increase the risk of false-negative results, particularly in patients with low NOTCH1(mut) allelic burden. This study compared two methods of the NOTCH1(mut)...

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Dettagli Bibliografici
Pubblicato in:Cancer Manag Res
Autori principali: Skórka, Katarzyna, Chojnacki, Michał, Masternak, Marta, Karczmarczyk, Agnieszka, Subocz, Edyta, Wawrzyniak, Ewa, Giannopoulos, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110254/
https://ncbi.nlm.nih.gov/pubmed/33986614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S302245
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