Targeted SHP-1 Silencing Modulates the Macrophage Phenotype, Leading to Metabolic Improvement in Dietary Obese Mice

Chronic over-nutrition promotes adipocyte hypertrophy that creates inflammatory milieu leading to macrophage infiltration and their phenotypic switching during obesity. The SH2 domain-containing protein tyrosine phosphatase 1 (SHP-1) has been identified as an important player in inflammatory disease...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Sharma, Yadhu, Ahmad, Altaf, Yavvari, Prabhu Srinivas, Kumar Muwal, Sandeep, Bajaj, Avinash, Khan, Farah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526246/
https://ncbi.nlm.nih.gov/pubmed/31108319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.04.020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados