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Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells

Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics—first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their in vit...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cells Int
Hauptverfasser: Tumangelova-Yuzeir, Kalina, Naydenov, Emanuil, Ivanova-Todorova, Ekaterina, Krasimirova, Ekaterina, Vasilev, Georgi, Nachev, Sevdalin, Kyurkchiev, Dobroslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525812/
https://ncbi.nlm.nih.gov/pubmed/31191680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6904638
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