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Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells

Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics—first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their in vit...

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Bibliografske podrobnosti
izdano v:Stem Cells Int
Main Authors: Tumangelova-Yuzeir, Kalina, Naydenov, Emanuil, Ivanova-Todorova, Ekaterina, Krasimirova, Ekaterina, Vasilev, Georgi, Nachev, Sevdalin, Kyurkchiev, Dobroslav
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525812/
https://ncbi.nlm.nih.gov/pubmed/31191680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6904638
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