MODELLING γ-H2AX FOCI INDUCTION TO MIMIC LIMITATIONS IN THE SCORING TECHNIQUE

An approach based on track-structure calculations has been developed to take account of artefacts occurring during γ-H2AX foci detection in 2D images of samples analyzed through immunocytochemistry. The need of this works stems from the observed saturation in foci yields measured after X-ray doses h...

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Bibliografiske detaljer
Udgivet i:Radiat Prot Dosimetry
Main Authors: Barbieri, Sofia, Baiocco, Giorgio, Babini, Gabriele, Morini, Jacopo, Friedland, Werner, Buonanno, Manuela, Grilj, Veljko, Brenner, David J, Ottolenghi, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525333/
https://ncbi.nlm.nih.gov/pubmed/30520984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rpd/ncy217
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