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Perturbational Gene-Expression Signatures for Combinatorial Drug Discovery

Cancer is a complex disease that relies on both oncogenic mutations and non-mutated genes for survival, and therefore coined as oncogene and non-oncogene addictions. The need for more effective combination therapies to overcome drug resistance in oncology has been increasingly recognized, but the id...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Huang, Chen-Tsung, Hsieh, Chiao-Hui, Chung, Yun-Hsien, Oyang, Yen-Jen, Huang, Hsuan-Cheng, Juan, Hsueh-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525321/
https://ncbi.nlm.nih.gov/pubmed/31102995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.04.039
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