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The phage T4 DNA ligase mediates bacterial chromosome DSBs repair as single component non-homologous end joining
DNA double-strand breaks (DSBs) are one of the most lethal forms of DNA damage that is not efficiently repaired in prokaryotes. Certain microorganisms can handle chromosomal DSBs using the error-prone non-homologous end joining (NHEJ) system and ultimately cause genome mutagenesis. Here, we demonstr...
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| Publicado no: | Synth Syst Biotechnol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
KeAi Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525309/ https://ncbi.nlm.nih.gov/pubmed/31193309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2019.04.001 |
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