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Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

Discovery of novel bioactive compounds is important not only for therapeutic purposes but also for understanding the mechanisms of biological processes. To screen bioactive compounds that affect nuclear morphology in marine organism extracts, we employed a microscopy-based assay using DNA staining o...

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Publicat a:Sci Rep
Autors principals: Hayashi-Takanaka, Yoko, Kina, Yuto, Nakamura, Fumiaki, Yamazaki, Shota, Harata, Masahiko, Soest, Rob W. M. van, Kimura, Hiroshi, Nakao, Yoichi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525181/
https://ncbi.nlm.nih.gov/pubmed/31101864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44036-2
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