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Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

Discovery of novel bioactive compounds is important not only for therapeutic purposes but also for understanding the mechanisms of biological processes. To screen bioactive compounds that affect nuclear morphology in marine organism extracts, we employed a microscopy-based assay using DNA staining o...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hayashi-Takanaka, Yoko, Kina, Yuto, Nakamura, Fumiaki, Yamazaki, Shota, Harata, Masahiko, Soest, Rob W. M. van, Kimura, Hiroshi, Nakao, Yoichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525181/
https://ncbi.nlm.nih.gov/pubmed/31101864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44036-2
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