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Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

Discovery of novel bioactive compounds is important not only for therapeutic purposes but also for understanding the mechanisms of biological processes. To screen bioactive compounds that affect nuclear morphology in marine organism extracts, we employed a microscopy-based assay using DNA staining o...

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Publicado no:Sci Rep
Main Authors: Hayashi-Takanaka, Yoko, Kina, Yuto, Nakamura, Fumiaki, Yamazaki, Shota, Harata, Masahiko, Soest, Rob W. M. van, Kimura, Hiroshi, Nakao, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525181/
https://ncbi.nlm.nih.gov/pubmed/31101864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44036-2
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