Adolescent Δ(9)-THC exposure and astrocyte-specific genetic vulnerability converge on NF-κB-COX-2 signaling to impair memory in adulthood.

BACKGROUND: Although several studies linked adolescent cannabis use to long-term cognitive dysfunction, there are negative reports too. The fact that not all users develop cognitive impairment suggests a genetic vulnerability to adverse effects of cannabis, which are attributed to action of delta-9-...

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Publicado no:Biol Psychiatry
Main Authors: Jouroukhin, Yan, Zhu, Xiaolei, Shevelkin, Alexey V., Hasegawa, Yuto, Abazyan, Bagrat, Saito, Atsushi, Pevsner, Jonathan, Kamiya, Atsushi, Pletnikov, Mikhail V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525084/
https://ncbi.nlm.nih.gov/pubmed/30219209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.07.024
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