TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis

FAM3C/Interleukin-like EMT Inducer (ILEI) is an oncogenic member of the FAM3 cytokine family and serves essential roles in both epithelial-mesenchymal transition (EMT) and breast cancer metastasis. ILEI expression levels are regulated through a non-canonical TGFβ signaling pathway by 3’-UTR-mediated...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Woosley, Alec N., Dalton, Annamarie C., Hussey, George S., Howley, Breege V., Mohanty, Bidyut K., Grelet, Simon, Dincman, Toros, Bloos, Sean, Olsen, Shaun K., Howe, Philip H.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525020/
https://ncbi.nlm.nih.gov/pubmed/30692635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0703-z
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