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TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis
FAM3C/Interleukin-like EMT Inducer (ILEI) is an oncogenic member of the FAM3 cytokine family and serves essential roles in both epithelial-mesenchymal transition (EMT) and breast cancer metastasis. ILEI expression levels are regulated through a non-canonical TGFβ signaling pathway by 3’-UTR-mediated...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525020/ https://ncbi.nlm.nih.gov/pubmed/30692635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0703-z |
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