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Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry

Control of cell size requires molecular size sensors that are coupled to the cell cycle. Rod-shaped fission yeast cells divide at a threshold size partly due to Cdr2 kinase, which forms nodes at the medial cell cortex where it inhibits the Cdk1-inhibitor Wee1. Pom1 kinase phosphorylates and inhibits...

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Pubblicato in:eLife
Autori principali: Allard, Corey A H, Opalko, Hannah E, Moseley, James B
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524964/
https://ncbi.nlm.nih.gov/pubmed/31050341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46003
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