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Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura

In this study, we investigated a case of pregnancy-onset thrombotic thrombocytopenic purpura (TTP). The patient had severely decreased ADAMTS13 ( a d isintegrin a nd m etalloprotease with t hrombo s pondin type 1 motif, member 13) activity levels during acute phase and the presence of inhibitory ant...

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Detalhes bibliográficos
Publicado no:TH Open
Main Authors: Roose, Elien, Tersteeg, Claudia, Demeersseman, Ruth, Schelpe, An-Sofie, Deforche, Louis, Pareyn, Inge, Vandenbulcke, Aline, Vandeputte, Nele, Dierickx, Daan, Voorberg, Jan, Deckmyn, Hans, De Meyer, Simon F., Vanhoorelbeke, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524854/
https://ncbi.nlm.nih.gov/pubmed/31249923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1615252
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